Are peroxisome proliferator-activated receptors new therapeutic targets in diabetic and non-diabetic nephropathies?
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چکیده
منابع مشابه
Are peroxisome proliferator-activated receptors new therapeutic targets in diabetic and non-diabetic nephropathies?
Helbich T, Tscholakoff D. Polyetiology of renal allograft dysfunction. Does calculation of the resistive index still make sense? Acta Radiol 1992; 33: 434–439 7. Scholbach T, Girelli E, Scholbach J. Dynamic tissue perfusion measurement: a novel tool in follow-up of renal transplants. Transplantation 2005; 79: 1711–1716 8. Nankivell BJ, Chapman JR, Gruenewald SM. Detection of chronic allograft n...
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Peroxisome proliferator-activated receptors (PPARs) are members of the ligand-activated nuclear hormone receptor superfamily of transcription factors that includes receptors for steroids, thyroid hormone, retinoic acid, and vitamin D. Upon activation in the cytoplasm, PPARs heterodimerize with retinoid X receptors (RXR) and form a complex that translocates to the nucleus and regulates gene expr...
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With a developing worldwide epidemic of diabetes mellitus, the renal complications associated with diabetes have become a serious health concern. Primary therapy for treating diabetic nephropathy is a multifactorial process. Peroxisome proliferator-activated receptor alpha (PPARα) agonists have been used primarily in clinical practice for the treatment of dyslipidemia and insulin resistance. Gi...
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2006
ISSN: 1460-2385,0931-0509
DOI: 10.1093/ndt/gfl448